Yang Yue, Lier Liu, Li-Jie Wu, Yiran Wu, Ling Wang, Fei Li, Junlin Liu, Gye-Won Han, Bo Chen, Xi Lin, Rebecca L Brouillette, Émile Breault, Jean-Michel Longpré, Songting Shi, Hui Lei, Philippe Sarret, Raymond C Stevens, Michael A Hanson, Fei Xu “Structural insight into apelin receptor-G protein stoichiometry” Nat Struct Mol Biol. 2022 Jul;29(7):688-697. doi: 10.1038/s41594-022-00797-5. Epub 2022 Jul 11.

C. Martin, L.E. Gimenez, S.Y. Williams, Y. Jing, Y. Wu, C. Hollanders, O. Van der Poorten, S. Gonzalez, K. Van Holsbeeck, S. Previti, A. Lamouroux, S. Zhao, D. Tourwe, R.C. Stevens, R.D. Cone, S. Ballet “Structure based design of melanocortin 4 receptor ligands based on the SHU-9119-hMC4R cocrystal structure.” J. Med. Chem. 64, 357-369 (2021). doi: 10.1021/acs.jmedchem.0c01620.

J. Singla, K.L. White, R.C. Stevens, F. Abler “Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography” J. Struct. Biol. Online 19 Mar (2021). doi: 10.1016/j.jsb.2021.107727.

Z. Wang, T. Gurlo, A.V. Matveyenko, D. Elashoff, P. Wang, M. Rosenberger, J.A. Junge, R.C. Stevens, K.L. White, S.E. Fraser, P.C. Butler “Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes” Commun. Biol. 4, 594 (2021). doi: 10.1038/s42003-021-02113-1.

F. Zhao, C. Zhang, Q. Zhou, K. Hang, X. Zou, Y. Chen, F. Wu, Q. Rao, A. Dai, W. Yin, D.D. Shen, Y. Zhang, T. Xia, R.C. Stevens, H.E. Xu, D. Yang, L. Zhao, M.W. Wang “Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor.” Elife 10, e68719 (2021). doi: 10.7554/eLife.68719.

J. Yu, L.E. Gimenez, C.C. Hernandez, Y. Wu, A.H. Wein, G.W. Han, K. McClary, S.R. Mittal, K. Burdsall, B. Stauch, L. Wu, S.N. Stevens, A. Peisley, S.Y. Williams, V. Chen, G.L. Millhauser, S. Zhao, R.D. Cone, R.C. Stevens “Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding” Science 368, 428-433 (2020). online 24 April 2020. doi: 10.1126/science.aaz8995. PMC7567314.

M. Audet, K. Villers, J. Velasquez, M. Chu, C. Hanson, R.C. Stevens “Small-scale approach for precrystallization screening in GPCR X-ray crystallography” Nat. Protoc. 15, 144-160 (2020). doi: 10.1038/s41596-019-0259-y.

R. Lamichhane, J.J. Liu, K.L. White, V. Katritch, R.C. Stevens, K. Wüthrich, D.P. Millar “Biased signaling in the G-protein-coupled receptor β2AR is governed by conformational exchange kinetics” Structure 28, 371-377 (2020). doi: 10.1016/j.str.2020.01.001. PMC7213800.

F. Wu, L. Yang, K. Hang, M. Laursen, L. Wu, G.W. Han, Q. Ren, N.K. Roed, G. Lin, M.A. Hanson, H. Jiang, M.W. Wang, S. Reedtz-Runge, G. Song, R.C. Stevens “Full-length human GLP-1 receptor structure without orthosteric ligands” Nat. Commun. 11, 1272 (2020). doi: 10.1038/s41467-020-14934-5. PMC7062719.

Y. Lu, S. Qin, B. Zhang, A. Dai, X. Cai, M. Ma, Z.G. Gao, D. Yang, R.C. Stevens, K.A. Jacobson, M.W. Wang, W. Shui “Accelerating the throughput of affinity mass spectrometry-based ligand screening towards a G protein-coupled receptor” Anal Chem 91, 8162-8169 (2019). doi: 10.1021/acs.analchem.9b00477. PMC6669887. doi: 10.1021/acs.analchem.oc00754 (correction 3 Mar 2020).